Publications

Publications of specific relevance to Applied Data Science
2020

Martín Guerrero SM, Casado P, Hijazi M, Rajeeve V, Plaza J, Abadía-Molina F, Navascués J, Cuadros MA,
Cutillas PR and Martín-Oliva D (2020).
PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability. Biochem J 10.1042/BCJ20200525
Akhtar N, Baig MW, Haq I-U, Rajeeve V and
Cutillas PR (2020).
Withanolide Metabolites Inhibit PI3K/AKT and MAPK Pro-Survival Pathways and Induce Apoptosis in Acute Myeloid Leukemia Cells. Biomedicines vol. 8, (9)
10.3390/biomedicines8090333
Xu R, Jones W, Wilcz-Villega E, Costa ASH, Rajeeve V, Bentham RB, Bryson K, Nagano A, Yaman B, Olendo Barasa S, Wang Y, Chelala C,
Cutillas P, Szabadkai G, Frezza C and Bianchi K (2020).
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism. Embo Reports vol. 21, (9)
10.15252/embr.201948260
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V,
Cutillas PR, Lobley AE, Wang J, Gea E, Ross-Adams H,
Bessant C, Lemoine NR, Jones LJ and Chelala C (2020).
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer. Nature Research (Part of Springer Nature) Npj Breast Cancer vol. 6, (1)
10.1038/s41523-020-00182-9
Kostaras E, Kaserer T, Lazaro G, Heuss SF, Hussain A, Casado P, Hayes A, Yandim C, Palaskas N, Yu Y, Schwartz B, Raynaud F, Chung YL,
Cutillas PR and Vivanco I (2020).
A systematic molecular and pharmacologic evaluation of AKT inhibitors reveals new insight into their biological activity. British Journal of Cancer vol. 123, (4) 542-555.
10.1038/s41416-020-0889-4
Patani H, Rushton MD, Higham J, Teijeiro SA, Oxley D,
Cutillas P, Sproul D and Ficz G (2020).
Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation. Nat Commun vol. 11, (1)
10.1038/s41467-020-17269-3
Wong PP, Muñoz-Félix JM, Hijazi M, Kim H, Robinson SD, De Luxán-Delgado B, Rodríguez-Hernández I, Maiques O, Meng YM, Meng Q, Bodrug N, Dukinfield MS, Reynolds LE, Elia G, Clear A, Harwood C, Wang Y, Campbell JJ, Singh R, Zhang P, Schall TJ, Matchett KP, Henderson NC, Szlosarek PW, Dreger SA, Smith S, Jones JL, Gribben JG,
Cutillas PR and Meier P (2020).
Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells. Cell vol. 181, (6) 1346-1363.e21.
10.1016/j.cell.2020.02.003
Invergo BM, Petursson B, Akhtar N, Bradley D, Giudice G, Hijazi M,
Cutillas P, Petsalaki E and Beltrao P (2020).
Prediction of Signed Protein Kinase Regulatory Circuits. Cell Syst vol. 10, (5) 384-396.e9.
10.1016/j.cels.2020.04.005
Demircioglu F, Wang J, Candido J, Costa ASH, Casado P, de Luxan Delgado B, Reynolds LE, Gomez-Escudero J, Newport E, Rajeeve V, Baker A-M, Roy-Luzarraga M,
Graham TA, Foster J, Wang Y, Campbell JJ, Singh R, Zhang P, Schall TJ, Balkwill FR, Sosabowski J,
Cutillas PR, Frezza C, Sancho P and Hodivala-Dilke K (2020).
Cancer associated fibroblast FAK regulates malignant cell metabolism. Nature Research (Part of Springer Nature) Nature Communications vol. 11, (1) 1290-1290.
10.1038/s41467-020-15104-3
Huang KW, Reebye V, Czysz K, Ciriello S, Dorman S, Reccia I, Lai HS, Peng L, Kostomitsopoulos N, Nicholls J, Habib RS, Tomalia DA, Sætrom P, Wilkes E,
Cutillas P, Rossi JJ and Habib NA (2020).
Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. Molecular Therapy - Nucleic Acids vol. 19, 361-370.
10.1016/j.omtn.2019.10.044
Fernández-Varo G, Perramón M, Carvajal S, Oró D, Casals E, Boix L, Oller L, Macías-Muñoz L, Marfà S, Casals G, Morales-Ruiz M, Casado P,
Cutillas PR, Bruix J, Navasa M, Fuster J, Garcia-Valdecasas JC, Pavel MC, Puntes V and Jiménez W (2020).
Bespoken nanoceria: A new effective treatment in experimental hepatocellular carcinoma. Hepatology 10.1002/hep.31139
Hijazi M, Smith R, Rajeeve V,
Bessant C and
Cutillas PR (2020).
Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring. Nature Research Nature Biotechnology 10.1038/s41587-019-0391-92019

Grey W, Casado-Izquierdo P,
Cutillas P and Bonnet D (2019).
Combination Therapy Targeting CKS1-Dependent Protein Degradation Reduces AML Burden Whilst Protecting Normal Haematopoietic Stem Cellsfrom Cytarabine Toxicity. Blood vol. 134, (Supplement_1) 2535-2535.
10.1182/blood-2019-121667
Edelmann J, Dokal A, Holzmann K, Britton DJ, Vilventhraraja E, Smith RJ, Cragg MS, Braun A, Döhner H,
Cutillas P and Gribben JG (2019).
Rituximab and Obinutuzumab Induce Direct B-Cell Death Via B-Cell Receptor (BCR) Signaling, but Rituximab Elicits Stronger BCR-Derived Pro-Survival Signals Diminishing Apoptosis. Blood vol. 134, (Supplement_1) 1579-1579.
10.1182/blood-2019-128704
Martín-Guerrero SM, Casado P, Muñoz-Gámez JA, Carrasco M-C, Navascués J, Cuadros MA, López-Giménez JF,
Cutillas PR and Martín-Oliva D (2019).
Poly(ADP-Ribose) Polymerase-1 inhibition potentiates cell death and phosphorylation of DNA damage response proteins in oxidative stressed retinal cells. Exp Eye Res vol. 188,
10.1016/j.exer.2019.107790
Alrawashdeh W, Jones R, Dumartin L, Radon TP,
Cutillas PR, Feakins RM, Dmitrovic B, Demir IE, Ceyhan GO and Crnogorac-Jurcevic T (2019).
Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modelling. Mol Oncol vol. 13, (5) 1075-1091.
10.1002/1878-0261.12463
Kostelnik KB, Barker A, Schultz C, Mitchell TP, Rajeeve V, White IJ, Aurrand-Lions M, Nourshargh S,
Cutillas P and Nightingale TD (2019).
Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration. Plos Biology vol. 17, (12)
10.1371/journal.pbio.30005542018

Naba A, Pearce OMT, Del Rosario A, Ma D, Ding H, Rajeeve V,
Cutillas PR, Balkwill FR and Hynes RO (2018).
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics. Journal of Proteome Research vol. 16, (8) 3083-3091.
10.1021/acs.jproteome.7b00191
Ferrandiz N, Barroso C, Telecan O, Shao N, Kim HM, Testori S, Faull P,
Cutillas P, Snijders AP, Colaiácovo MP and Martinez-Perez E (2018).
Erratum to: Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis (Nature Communications, (2018), 9, 1, (834), 10.1038/s41467-018-03229-5). Nature Communications vol. 9, (1)
10.1038/s41467-018-05848-4
Ferrandiz N, Barroso C, Telecan O, Shao N, Kim HM, Testori S, Faull P,
Cutillas P, Snijders AP, Colaiácovo MP and Martinez-Perez E (2018).
Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. Elegans oocyte meiosis. Nature Communications vol. 9, (1)
10.1038/s41467-018-03229-5
Arnandis T, Monteiro P, Adams SD, Bridgeman VL, Rajeeve V, Gadaleta E, Marzec J,
Chelala C, Malanchi I,
Cutillas PR and Godinho SA (2018).
Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion. Developmental Cell vol. 47, (4) 409-424.e9.
10.1016/j.devcel.2018.10.026
Angulo-Urarte A, Casado P, Castillo SD, Kobialka P, Kotini MP, Figueiredo AM, Castel P, Rajeeve V, Milà-Guasch M, Millan J, Wiesner C, Serra H, Muixi L, Casanovas O, Viñals F, Affolter M, Gerhardt H, Huveneers S, Belting H-G,
Cutillas PR and Graupera M (2018).
Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility. Nat Commun vol. 9, (1)
10.1038/s41467-018-07172-3
Simon T, Pinioti S, Schellenberger P, Rajeeve V, Wendler F,
Cutillas PR, King A, Stebbing J and Giamas G (2018).
Shedding of bevacizumab in tumour cells-derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma. Mol Cancer vol. 17, (1)
10.1186/s12943-018-0878-x
Casado P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Iqbal S, Marfa S, Lea N, Best S, Gribben J, Fitzgibbon J and
Cutillas PR (2018).
Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells. Leukemia vol. 32, (8) 1818-1822.
10.1038/s41375-018-0032-1
Tummala H, Dokal AD, Walne A, Ellison A, Cardoso S, Amirthasigamanipillai S, Kirwan M, Browne I, Sidhu JK, Rajeeve V, Rio-Machin A, Seraihi AA, Duncombe AS, Jenner M, Smith OP, Enright H, Norton A, Aksu T, Özbek NY, Pontikos N,
Cutillas P, Dokal I and Vulliamy T (2018).
Genome instability is a consequence of transcription deficiency in patients with bone marrow failure harboring biallelic ERCC6L2 variants. Proc Natl Acad Sci U S A vol. 115, (30) 7777-7782.
10.1073/pnas.1803275115
Fearon AE, Carter EP, Clayton NS, Wilkes EH, Baker AM, Kapitonova E, Bakhouche BA, Tanner Y, Wang J, Gadaleta E,
Chelala C, Moore KM, Marshall JF, Chupin J, Schmid P, Jones JL, Lockley M,
Cutillas PR and Grose RP (2018).
PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer. Cell Reports vol. 22, (9) 2469-2481.
10.1016/j.celrep.2018.02.0282017

Casado P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Iqbal S, Marfa S, Lea N, Best S, Gribben J, Fitzgibbon J and
Cutillas PR (2017).
Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells. Leukemia 10.1038/leu.2017.349
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD,
Chelala C,
Cutillas PR, Lockley M,
Bessant C, Knight M and Balkwill FR (2017).
Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov 10.1158/2159-8290.CD-17-0284
Kyprianou N, Gregory L, Vignola ML, Marinelli E, Gualtieri A, Scagliotti V, Davis S, Casado P, Rajeeve V,
Cutillas P, Gevers E, Dattani M and Gaston-Massuet C (2017).
The MAPK effector B-Raf is essential for hypothalamic-pituitary axis development and activating mutations in BRAF Cause Congenital hypopituitarism. Endocrine Abstracts 10.1530/endoabs.51.oc4.4
Dermit M, Dokal A and
Cutillas PR (2017).
Approaches to identify kinase dependencies in cancer signalling networks. Febs Lett vol. 591, (17) 2577-2592.
10.1002/1873-3468.12748
Wilkes EH, Casado P, Rajeeve V and
Cutillas PR (2017).
Kinase activity ranking using phosphoproteomics data (KARP) quantifies the contribution of protein kinases to the regulation of cell viability. Mol Cell Proteomics vol. 16, (9) 1694-1704.
10.1074/mcp.O116.064360
Yuzugulen J, Douthwaite JA, Wood EG, Villar IC, Patel NSA, Jegard J, Gaertner H, Rossitto-Borlat I, Rose K, Hartley O,
Cutillas PR, Ahluwalia A and Corder R (2017).
Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1. Sci Rep vol. 7, (1) 4956-4956.
10.1038/s41598-017-05365-22016

Dermit M, Casado P, Rajeeve V, Wilkes EH, Foxler DE, Campbell H, Critchlow S, Sharp TV, Gribben JG, Unwin R and
Cutillas PR (2016).
Oxidative stress downstream of mTORC1 but not AKT causes a proliferative defect in cancer cells resistant to PI3K inhibition. Nature Publishing Group Oncogene 10.1038/onc.2016.435
Afzal TA, Luong LA, Chen D, Zhang C, Yang F, Chen Q, An W, Wilkes E, Yashiro K,
Cutillas PR, Zhang L and Xiao Q (2016).
NCK Associated Protein 1 Modulated by miRNA-214 Determines Vascular Smooth Muscle Cell Migration, Proliferation, and Neointima Hyperplasia. Wiley Journal of The American Heart Association vol. 5, (12) e004629-e004629.
10.1161/JAHA.116.004629
Villoria MT, Ramos F, Dueñas E, Faull P,
Cutillas PR and Clemente-Blanco A (2016).
Stabilization of the metaphase spindle by Cdc14 is required for recombinational DNA repair. Embo Press Embo J vol. 36, (1) 79-101.
10.15252/embj.201593540
Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamas K, Hadgraft N, Martin ED, Worthington J, Rudyk O,
Rodriguez Cutillas P, Cuello F, Shattock MJ, Marber MS, Conte MR, Greenstein A, Greensmith DJ, Venetucci L, Timms JF and Eaton P (2016).
Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response. Nature Publishing Group: Nature Communications Nature Communications vol. 7, 13187-13187.
10.1038/ncomms13187
Casado P, Hijazi M, Britton D and
Cutillas PR (2016).
Impact of phosphoproteomics in the translation of kinase targeted therapies. Wiley-Vch Verlag Proteomics 10.1002/pmic.201600235
Sciacovelli M, Gonçalves E, Johnson TI, Zecchini VR, da Costa ASH, Gaude E, Drubbel AV, Theobald SJ, Abbo SR, Tran MGB, Rajeeve V, Cardaci S, Foster S, Yun H,
Cutillas P, Warren A, Gnanapragasam V, Gottlieb E, Franze K, Huntly B, Maher ER, Maxwell PH, Saez-Rodriguez J and Frezza C (2016).
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition. Nature vol. 537, (7621) 544-547.
10.1038/nature19353
Montfort A, Pearce OMT, Maniati E, Vincent B, Bixby LM, Bo hm S, Dowe T, Wilkes EH, Chakravarty P, Thompson R, Topping J,
Cutillas PR, Lockley M, Serody JS, Capasso M and Balkwill FR (2016).
A strong B cell response is part of the immune landscape in human high-grade serous ovarian metastases. American Association For Cancer Research Clinical Cancer Research 10.1158/1078-0432.CCR-16-0081
Kulbe H, Iorio F, Chakravarty P, Milagre CS, Moore R, Thompson RG, Everitt G, Canosa M, Montoya A, Drygin D, Braicu I, Sehouli J, Saez-Rodriguez J,
Cutillas PR and Balkwill FR (2016).
Integrated transcriptomic and proteomic analysis identifies protein kinase CK2 as a key signaling node in an inflammatory cytokine network in ovarian cancer cells. Oncotarget vol. 7, (13) 15648-15661.
10.18632/oncotarget.7255
Quétier I, Marshall JJT, Spencer-Dene B, Lachmann S, Casamassima A, Franco C, Escuin S, Worrall JT, Baskaran P, Rajeeve V, Howell M, Copp AJ, Stamp G, Rosewell I,
Cutillas P, Gerhardt H, Parker PJ and Cameron AJM (2016).
Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion. Cell Reports vol. 14, (3) 440-448.
10.1016/j.celrep.2015.12.049
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J and Algül H (2016).
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy vol. 12, (1) 1-222.
10.1080/15548627.2015.11003562015

Terfve CDA, Wilkes EH, Casado P,
Cutillas PR and Saez-Rodriguez J (2015).
Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data. Nat Commun vol. 6,
10.1038/ncomms9033
Carretero L, Llavona P, López-Hernández A, Casado P,
Cutillas PR, de la Peña P, Barros F and Domínguez P (2015).
ERK and RSK are necessary for TRH-induced inhibition of r-ERG potassium currents in rat pituitary GH3 cells. Cell Signal vol. 27, (9) 1720-1730.
10.1016/j.cellsig.2015.05.014
Wilkes EH, Terfve C, Gribben JG, Saez-Rodriguez J and
Cutillas PR (2015).
Empirical inference of circuitry and plasticity in a kinase signaling network. Proc Natl Acad Sci U S A vol. 112, (25) 7719-7724.
10.1073/pnas.1423344112
Cutillas PR (2015).
Role of phosphoproteomics in the development of personalized cancer therapies. Proteomics Clin Appl vol. 9, (3-4) 383-395.
10.1002/prca.201400104
Hall AM, Vilasi A, Garcia-Perez I, Lapsley M, Alston CL, Pitceathly RDS, McFarland R, Schaefer AM, Turnbull DM, Beaumont NJ, Hsuan JJ,
Cutillas PR, Lindon JC, Holmes E, Unwin RJ, Taylor RW, Gorman GS, Rahman S and Hanna MG (2015).
The urinary proteome and metabonome differ from normal in adults with mitochondrial disease. Kidney Int vol. 87, (3) 610-622.
10.1038/ki.2014.297
Rotival M, Ko J-H, Srivastava PK, Kerloc'h A, Montoya A, Mauro C#29345#, Faull P, Cutillas PR#21840#, Petretto E and Behmoaras J (2015).
Integrating phosphoproteome and transcriptome reveals new determinants of macrophage multinucleation. Mol Cell Proteomics vol. 14, (3) 484-498.
10.1074/mcp.M114.0438362014

Wilkes EH, Casado P and
Cutillas PR (2014).
Approaches for measuring signalling plasticity in the context of resistance to targeted cancer therapies. Biochem Soc Trans vol. 42, (4) 791-797.
10.1042/BST20140029
Rajeeve V, Vendrell I, Wilkes E, Torbett N and
Cutillas PR (2014).
Cross-species proteomics reveals specific modulation of signaling in cancer and stromal cells by phosphoinositide 3-kinase (PI3K) inhibitors. Mol Cell Proteomics vol. 13, (6) 1457-1470.
10.1074/mcp.M113.035204
Casado P, Bilanges B, Rajeeve V, Vanhaesebroeck B and
Cutillas PR (2014).
Environmental Stress Affects the Activity of Metabolic and Growth Factor Signaling Networks and Induces Autophagy Markers in MCF7 Breast Cancer Cells. Molecular & Cellular Proteomics vol. 13, (3) 836-848.
10.1074/mcp.M113.0347512013

Yuzugulen J, Wood EG, Villar IC, Douthwaite JA, Patel NSAI, Jegard J, Montoya A,
Cutillas P, Gaertner H, Rossitto-Borlat I, Rose K, Hartley O, Ahluwalia A and Corder R (2013).
Characterisation of the “Endothelin-Like Domain Peptide” (ELDP) co-synthesised with Endothelin-1 from the EDN1 gene. Life Sciences vol. 93, (25-26)
10.1016/j.lfs.2013.12.037
Lumb S, Torbett N, Vendrell I, Turner H, Page M, Hales P, Maloney A, Vanhaesebroeck B,
Cutillas P and Shock A (2013).
THU0045 Epratuzumab, an Antibody Targeting CD22 on B Cells, Induces Phosphoprotein Changes Following B-Cell Receptor Activation in Vitro. Annals of The Rheumatic Diseases vol. 72, (Suppl 3)
10.1136/annrheumdis-2013-eular.573
Casado P, Alcolea MP, Iorio F, Rodríguez-Prados J-C, Vanhaesebroeck B, Saez-Rodriguez J, Joel S and
Cutillas PR (2013).
Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitors. Genome Biol vol. 14, (4)
10.1186/gb-2013-14-4-r37
Casado P, Rodriguez-Prados J-C, Cosulich SC, Guichard S, Vanhaesebroeck B, Joel S and
Cutillas PR (2013).
Kinase-substrate enrichment analysis provides insights into the heterogeneity of signaling pathway activation in leukemia cells. Sci Signal vol. 6, (268)
10.1126/scisignal.2003573
Rajeeve V, Pearce W, Cascante M, Vanhaesebroeck B and
Cutillas PR (2013).
Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth. Biochem J vol. 450, (3) 619-628.
10.1042/BJ20121525
Alrawashdeh W, Jones R,
Cutillas P, Wijesuriya N and Crnogorac-Jurcevic T (2013).
Proteomic analysis of perineural invasion in pancreatic adenocarcinoma reveals up-regulation of neurosecretory protein VGF in invaded nerves. Pancreatology vol. 13, (2)
10.1016/j.pan.2012.12.0662012

Beltran L, Casado P, Rodríguez-Prados J-C and
Cutillas PR (2012).
Global profiling of protein kinase activities in cancer cells by mass spectrometry. J Proteomics vol. 77, 492-503.
10.1016/j.jprot.2012.09.029
Cappadona S, Baker PR,
Cutillas PR, Heck AJR and van Breukelen B (2012).
Current challenges in software solutions for mass spectrometry-based quantitative proteomics. Amino Acids vol. 43, (3) 1087-1108.
10.1007/s00726-012-1289-8
Alcolea MP, Casado P, Rodríguez-Prados J-C, Vanhaesebroeck B and
Cutillas PR (2012).
Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance. Mol Cell Proteomics vol. 11, (8) 453-466.
10.1074/mcp.M112.017483
Kitromilidou C, McDonald D,
Cutillas P, Ghazaly E, Perry J, Csaba B, Joel S and Powles T (2012).
Abstract 1792: The potential role of targeting HER1-4 in bladder cancer. 10.1158/1538-7445.am2012-1792
Kulbe H, Chakravarty P, Moore R, Iorio F, Montoya A, Saez-Rodriguez J,
Cutillas P and Balkwill F (2012).
Abstract 49: Targeting the TNF network in human ovarian cancer - A systems biology approach. 10.1158/1538-7445.am2012-49
Burling KA,
Cutillas PR, Church D, Lapsley M and Norden AGW (2012).
Analysis of molecular forms of urine Retinol-Binding Protein in Fanconi Syndrome and design of an accurate immunoassay. Clinica Chimica Acta vol. 413, (3-4) 483-489.
10.1016/j.cca.2011.11.0072011

Worthington J,
Cutillas PR and Timms JF (2011).
IMAC/TiO2 enrich for peptide modifications other than phosphorylation: Implications for chromatographic choice and database searching in phosphoproteomics. Proteomics vol. 11, (23) 4583-4587.
10.1002/pmic.201100143
Beltran L, Chaussade C, Vanhaesebroeck B and
Cutillas PR (2011).
Calpain interacts with class IA phosphoinositide 3-kinases regulating their stability and signaling activity. Proc Natl Acad Sci U S A vol. 108, (39) 16217-16222.
10.1073/pnas.1107692108
Montoya A, Beltran L, Casado P, Rodríguez-Prados J-C and
Cutillas PR (2011).
Characterization of a TiO₂ enrichment method for label-free quantitative phosphoproteomics. Methods vol. 54, (4) 370-378.
10.1016/j.ymeth.2011.02.004
Cutillas PR and Jørgensen C (2011).
Biological signalling activity measurements using mass spectrometry. Biochem J vol. 434, (2) 189-199.
10.1042/BJ20101974
Casado P and
Cutillas PR (2011).
A self-validating quantitative mass spectrometry method for assessing the accuracy of high-content phosphoproteomic experiments. Mol Cell Proteomics vol. 10, (1)
10.1074/mcp.M110.0030792010

Alcolea MP and
Cutillas PR (2010).
In-depth analysis of protein phosphorylation by multidimensional ion exchange chromatography and mass spectrometry. Methods Mol Biol vol. 658, 111-126.
10.1007/978-1-60761-780-8_62009
Cutillas PR (2009).
Quantifying oncogenic signalling by mass spectrometry. Amino Acids vol. 37, (4) 762-762.

Alcolea MP, Kleiner O and
Cutillas PR (2009).
Increased confidence in large-scale phosphoproteomics data by complementary mass spectrometric techniques and matching of phosphopeptide data sets. J Proteome Res vol. 8, (8) 3808-3815.
10.1021/pr800955n
Quintana LF, Campistol JM, Alcolea MP, Banon-Maneus E, Sole-Gonzalez A and
Cutillas PR (2009).
Application of Label-free Quantitative Peptidomics for the Identification of Urinary Biomarkers of Kidney Chronic Allograft Dysfunction. Mol Cell Proteomics vol. 8, (7) 1658-1673.
10.1074/mcp.M900059-MCP2002008

Vilasi A,
Cutillas PR and Unwin RJ (2008).
Application of proteomic techniques to the study of urine and renal tissue. Proteom Clin Appl vol. 2, (12) 1564-1574.
10.1002/prca.200800035
Graupera M, Guillermet-Guibert J, Foukas LC, Phng LK, Cain RJ, Salpekar A, Pearce W, Meek S, Millan J,
Cutillas PR, Smith AJH, Ridley AJ, Ruhrberg C, Gerhardt H and Vanhaesebroeck B (2008).
Angiogenesis selectively requires the p110 alpha isoform of PI3K to control endothelial cell migration. Nature vol. 453, (7195) 662-U9.
10.1038/nature068922007
Cutillas PR and Vanhaesebroeck B (2007).
Quantitative profile of five murine core proteomes using label-free functional proteomics. Mol Cell Proteomics vol. 6, (9) 1560-1573.
10.1074/mcp.M700037-MCP200
Vilasi A,
Cutillas PR, Maher AD, Zirah SFM, Capasso G, Norden AWG, Holmes E, Nicholson JK and Unwin RJ (2007).
Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome. Am J Physiol Renal Physiol vol. 293, (2) F456-F467.
10.1152/ajprenal.00095.2007
Cutillas PR and Vanhaesebroeck B (2007).
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