Publications

Publications of specific relevance to Applied Data Science
2019

Conti D, Gul P, Islam A, Martín-Durán JM, Pickersgill RW and
Draviam VM (2019).
Kinetochores attached to microtubule-ends are stabilised by astrin bound pp1 to ensure proper chromosome segregation. Elife Sciences Publications Ltd Elife vol. 8,
10.7554/eLife.49325
Hart M, Zulkipli I, Shrestha RL, Dang D, Conti D, Gul P, Kujawiak I and
Draviam VM (2019).
MARK2/Par1b kinase present at centrosomes and retraction fibres corrects spindle off-centring induced by actin disassembly. The Royal Society Open Biology vol. 9, (6)
10.1098/rsob.1802632018

Zulkipli I, Clark J, HART M, Shrestha R, GUL P,
DANG D, Kasichiwin T, Kujawiak I, SASTRY N and
DRAVIAM VM (2018).
Spindle rotation in human cells is reliant on a MARK2-mediated equatorial spindle centering mechanism. Rockefeller University Press Journal of Cell Biology 10.1083/jcb.2018041662017

Shrestha RL, Conti D, Tamura N, Braun D, Ramalingam RA, Cieslinski K, Ries J and
Draviam VM (2017).
Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells. Macmillan Publishers Limited, Part of Springer Nature. Nat Commun vol. 8, (1) 150-150.
10.1038/s41467-017-00209-z2016

Hiroi N,
Draviam VM and Funahashi A (2016).
Editorial: Quantitative Biology: Dynamics of Living Systems. Frontiers Media Sa Front Physiol vol. 7,
10.3389/fphys.2016.00196
Patel H, Stavrou I, Shrestha RL,
Draviam V, Frame MC and Brunton VG (2016).
Kindlin1 regulates microtubule function to ensure normal mitosis. Journal of Molecular Cell Biology vol. 8, (4) 338-348.
10.1093/jmcb/mjw0092015

Iorio F, Shrestha RL, Levin N, Boilot V, Garnett MJ, Saez-Rodriguez J and
Draviam VM (2015).
A semi-supervised approach for refining transcriptional signatures of drug response and repositioning predictions. Plos One vol. 10, (10)
10.1371/journal.pone.0139446
Corrigan AM, Shrestha R,
Draviam VM and Donald AM (2015).
Modeling of Noisy Spindle Dynamics Reveals Separable Contributions to Achieving Correct Orientation. Biophysical Journal vol. 109, (7) 1398-1409.
10.1016/j.bpj.2015.08.014
Tamura N, Simon JE, Nayak A, Shenoy R, Hiroi N, Boilot V, Funahashi A and
Draviam VM (2015).
A proteomic study of mitotic phase-Specific interactors of EB1 reveals a role for SXIP-Mediated protein interactions in anaphase onset. Biology Open vol. 4, (2) 155-169.
10.1242/bio.201410413
Ochi T, Blackford AN, Coates J, Jhujh S, Mehmood S, Tamura N, Travers J, Wu Q,
Draviam VM, Robinson CV, Blundell TL and Jackson SP (2015).
PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science vol. 347, (6218) 185-188.
10.1126/science.1261971
Nakai Y, Ozeki M, Hiraiwa T, Tanimoto R, Funahashi A, Hiroi N, Taniguchi A, Nonaka S, Boilot V, Shrestha R, Clark J, Tamura N,
Draviam VM and Oku H (2015).
High-speed microscopy with an electrically tunable lens to image the dynamics of in vivo molecular complexes. Review of Scientific Instruments vol. 86, (1)
10.1063/1.49053302014

Shrestha RL, Tamura N, Fries A, Levin N, Clark J and
Draviam VM (2014).
TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes. Open Biology vol. 4, (JUNE)
10.1098/rsob.130108
Chin-Hui-Men S, Nandra K, Clark J and
Draviam VM (2014).
Need for multi-scale systems to identify spindle orientation regulators relevant to tissue disorganisation in solid cancers. Frontiers in Physiology vol. 5 JUL,
10.3389/fphys.2014.002782013

Shrestha RL and
Draviam VM (2013).
Erratum: Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK (Current Biology (2013) 23 (1514-1526)). Current Biology vol. 23, (23) 2440-2441.
10.1016/j.cub.2013.11.015
Shrestha RL and
Draviam VM (2013).
Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins cenp-e and MCAK. Current Biology vol. 23, (16) 1514-1526.
10.1016/j.cub.2013.06.040
Corrigan AM, Shrestha RL, Zulkipli I, Hiroi N, Liu Y, Tamura N, Yang B, Patel J, Funahashi A, Donald A and
Draviam VM (2013).
Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance. Cell Cycle vol. 12, (16) 2643-2655.
10.4161/cc.25671
Draviam VM, Funahashi A, Hiroi N, Kimura A and Kobayashi TJ (2013).
Meeting report of the international workshop on quantitative biology 2012: Mesoscopic and microscopic worlds meet. Frontiers in Physiology vol. 3 JAN,
10.3389/fphys.2012.004792012

Tamura N and
Draviam VM (2012).
Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles. Open Biology vol. 2, (NOV)
10.1098/rsob.1201322009

Pagliuca C,
Draviam VM, Marco E, Sorger PK and De Wulf P (2009).
Roles for the conserved Spc105p/Kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint. Plos One vol. 4, (10)
10.1371/journal.pone.0007640
McAinsh AD, Meraldi P,
Draviam VM, Toso A and Sorger PK (2009).
The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation (The EMBO Journal (2006) 25 (4033-4049) DOI:10.1038/sj.emboj.7601293). Embo Journal vol. 28, (9)
10.1038/emboj.2009.942008

Foijer F,
Draviam VM and Sorger PK (2008).
Studying chromosome instability in the mouse. Biochimica Et Biophysica Acta - Reviews On Cancer vol. 1786, (1) 73-82.
10.1016/j.bbcan.2008.07.0042007

Stegmeier F, Rape M,
Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW and Elledge SJ (2007).
Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities. Nature vol. 447, (7141) 876-881.
Draviam VM, Stegmeier F, Nalepa G, Sowa ME, Chen J, Liang A, Hannon GJ, Sorger PK, Harper JW and Elledge SJ (2007).
A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling. Nature Cell Biology vol. 9, (5) 556-564.
10.1038/ncb1569
Stegmeier F, Rape M,
Draviam VM, Nalepa G, Sowa ME, Ang XL, McDonald ER, Li MZ, Hannon GJ, Sorger PK, Kirschner MW, Harper JW and Elledge SJ (2007).
Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities. Nature vol. 446, (7138) 876-881.
10.1038/nature05694
Basto R, Gergely F,
Draviam VM, Ohkura H, Liley K and Raff JW (2007).
Hsp90 is required to localise cyclin B and Msps/ch-TOG to the mitotic spindle in Drosophila and humans. Journal of Cell Science vol. 120, (7) 1278-1287.
10.1242/jcs.0006042006

McAinsh AD, Meraldi P,
Draviam VM, Toso A and Sorger PK (2006).
The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation. Embo Journal vol. 25, (17) 4033-4049.
10.1038/sj.emboj.7601293
Draviam VM, Shapiro I, Aldridge B and Sorger PK (2006).
Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells. Embo Journal vol. 25, (12) 2814-2827.
10.1038/sj.emboj.76011682004
Draviam VM, Xie S and Sorger PK (2004).
Chromosome segregation and genomic stability. Current Opinion in Genetics and Development vol. 14, (2) 120-125.
10.1016/j.gde.2004.02.0072003

Gergely F,
Draviam VM and Raff JW (2003).
The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells. Genes and Development vol. 17, (3) 336-341.
10.1101/gad.2456032001
Draviam VM, Orrechia S, Lowe M, Pardi R and Pines J (2001).
The localization of human cyclins B1 and B2 determines CDK1 substrate specificity and neither enzyme requires MEK to disassemble the Golgi apparatus. Journal of Cell Biology vol. 152, (5) 945-958.
10.1083/jcb.152.5.945